ORUKA THERAPEUTICS INC

Ticker: ORKA CUSIP: 687604108 Class: 0

Avidity Partners Management LP's Holding History (CIK: 0001791827)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 660,424 Value ($000) $20,017 Avg Close $27.86 Range $18.19 - $32.64

Q3 2025

Shares 660,424 Value ($000) $12,700 Avg Close $14.82 Range $10.97 - $20.00

Q2 2025

Shares 352,124 Value ($000) $3,947 Avg Close $10.42 Range $5.49 - $13.70

Q1 2025

Shares 352,124 Value ($000) $3,613 Avg Close $12.47 Range $9.44 - $21.32

Q4 2024

Shares 352,124 Value ($000) $6,828 Avg Close $24.40 Range $17.64 - $31.13

Q3 2024

Shares 790,926 Value ($000) $19,386 Avg Close $34.79 Range $21.72 - $52.32

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	660,424	$20,017	$27.86	$18.19 - $32.64
Q3 2025	660,424	$12,700	$14.82	$10.97 - $20.00
Q2 2025	352,124	$3,947	$10.42	$5.49 - $13.70
Q1 2025	352,124	$3,613	$12.47	$9.44 - $21.32
Q4 2024	352,124	$6,828	$24.40	$17.64 - $31.13
Q3 2024	790,926	$19,386	$34.79	$21.72 - $52.32