ORUKA THERAPEUTICS INC

Ticker: ORKA CUSIP: 687604108 Class: 0

Paradigm Biocapital Advisors LP's Holding History (CIK: 0001855655)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 1,710,316 Value ($000) $51,840 Avg Close $27.86 Range $18.19 - $32.64

Q4 2024

Shares 819,660 Value ($000) $15,893 Avg Close $24.40 Range $17.64 - $31.13

Q3 2024

Shares 719,660 Value ($000) $17,639 Avg Close $34.79 Range $21.72 - $52.32

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	1,710,316	$51,840	$27.86	$18.19 - $32.64
Q4 2024	819,660	$15,893	$24.40	$17.64 - $31.13
Q3 2024	719,660	$17,639	$34.79	$21.72 - $52.32