PALISADE BIO INC

Ticker: PALI CUSIP: 696389402 Class: COM

TWO SIGMA SECURITIES, LLC's Holding History (CIK: 0001450144)

Note: Option positions (PUT/CALL) are excluded.

Q3 2025

Shares 29,406 Value ($000) $25 Avg Close $0.78 Range $0.53 - $1.90

Q2 2025

Shares 15,969 Value ($000) $11 Avg Close $0.72 Range $0.60 - $1.05

Q1 2025

Shares 14,153 Value ($000) $10 Avg Close $1.18 Range $0.64 - $2.59

Period	Shares	Value ($000)	Average Close	Price Range
Q3 2025	29,406	$25	$0.78	$0.53 - $1.90
Q2 2025	15,969	$11	$0.72	$0.60 - $1.05
Q1 2025	14,153	$10	$1.18	$0.64 - $2.59