PIERIS PHARMACEUTICALS INC

CUSIP: 720795103 Class: COMMON

SPHERA FUNDS MANAGEMENT LTD.'s Holding History (CIK: 0001496201)

Note: Option positions (PUT/CALL) are excluded.

Q1 2021
Shares 650,000 Value ($000) $1,671 Avg Close — Range —
Q4 2020
Shares 550,000 Value ($000) $1,375 Avg Close — Range —
Q4 2018
Shares 700,000 Value ($000) $1,862 Avg Close — Range —
Q3 2018
Shares 904,686 Value ($000) $5,066 Avg Close — Range —
Q2 2018
Shares 842,632 Value ($000) $4,272 Avg Close — Range —
Q1 2018
Shares 800,000 Value ($000) $5,456 Avg Close — Range —
Q4 2017
Shares 800,000 Value ($000) $6,040 Avg Close — Range —
Q3 2017
Shares 1,000,000 Value ($000) $5,760 Avg Close — Range —
Q2 2017
Shares 1,100,000 Value ($000) $5,566 Avg Close — Range —
Q1 2017
Shares 1,000,000 Value ($000) $2,600 Avg Close — Range —
Q4 2016
Shares 810,000 Value ($000) $1,134 Avg Close — Range —
Q3 2016
Shares 810,000 Value ($000) $1,482 Avg Close — Range —
Q2 2016
Shares 810,000 Value ($000) $1,304 Avg Close — Range —
Q1 2016
Shares 810,000 Value ($000) $1,539 Avg Close — Range —
Q4 2015
Shares 810,000 Value ($000) $1,855 Avg Close — Range —
Q3 2015
Shares 900,000 Value ($000) $1,647 Avg Close — Range —
Q2 2015
Shares 1,200,000 Value ($000) $3,300 Avg Close — Range —