PRAXIS PRECISION MEDICINES I

Ticker: PRAX CUSIP: 74006W207 Class: Common Stock

Jefferies Financial Group Inc.'s Holding History (CIK: 0000096223)

Note: Option positions (PUT/CALL) are excluded.

Q3 2025

Shares 2,000 Value ($000) $106 Avg Close $48.49 Range $37.19 - $61.03

Q2 2025

Shares 5,000 Value ($000) $210 Avg Close $38.08 Range $26.70 - $46.93

Period	Shares	Value ($000)	Average Close	Price Range
Q3 2025	2,000	$106	$48.49	$37.19 - $61.03
Q2 2025	5,000	$210	$38.08	$26.70 - $46.93