PRAXIS PRECISION MEDICINES I

Ticker: PRAX CUSIP: 74006W207 Class: Common Stock

GLENMEDE TRUST CO NA's Holding History (CIK: 0000314949)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 6,288 Value ($000) $1,853 Avg Close $186.22 Range $50.31 - $317.72

Q4 2024

Shares 3,809 Value ($000) $293 Avg Close $72.36 Range $55.33 - $86.93

Q3 2024

Shares 4,173 Value ($000) $240 Avg Close $54.02 Range $38.99 - $63.93

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	6,288	$1,853	$186.22	$50.31 - $317.72
Q4 2024	3,809	$293	$72.36	$55.33 - $86.93
Q3 2024	4,173	$240	$54.02	$38.99 - $63.93