PRAXIS PRECISION MEDICINES I

Ticker: PRAX CUSIP: 74006W207 Class: Common Stock

DIMENSIONAL FUND ADVISORS LP's Holding History (CIK: 0000354204)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 23,543 Value ($000) $6,939 Avg Close $186.22 Range $50.31 - $317.72

Q3 2025

Shares 37,414 Value ($000) $1,983 Avg Close $48.49 Range $37.19 - $61.03

Q4 2024

Shares 4,544 Value ($000) $350 Avg Close $72.36 Range $55.33 - $86.93

Q3 2024

Shares 5,089 Value ($000) $293 Avg Close $54.02 Range $38.99 - $63.93

Q2 2024

Shares 6,888 Value ($000) $284 Avg Close $47.26 Range $33.01 - $63.00

Q1 2024

Shares 15,040 Value ($000) $918 Avg Close $44.86 Range $20.50 - $67.21

Q4 2023

Shares 13,710 Value ($000) $305 Avg Close $18.01 Range $13.01 - $27.60

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	23,543	$6,939	$186.22	$50.31 - $317.72
Q3 2025	37,414	$1,983	$48.49	$37.19 - $61.03
Q4 2024	4,544	$350	$72.36	$55.33 - $86.93
Q3 2024	5,089	$293	$54.02	$38.99 - $63.93
Q2 2024	6,888	$284	$47.26	$33.01 - $63.00
Q1 2024	15,040	$918	$44.86	$20.50 - $67.21
Q4 2023	13,710	$305	$18.01	$13.01 - $27.60