PRAXIS PRECISION MEDICINES I

Ticker: PRAX CUSIP: 74006W207 Class: Common Stock

AMERIPRISE FINANCIAL INC's Holding History (CIK: 0000820027)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 22,715 Value ($000) $6,695 Avg Close $186.22 Range $50.31 - $317.72

Q1 2025

Shares 5,408 Value ($000) $205 Avg Close $62.45 Range $30.01 - $91.83

Q4 2024

Shares 3,227 Value ($000) $248 Avg Close $72.36 Range $55.33 - $86.93

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	22,715	$6,695	$186.22	$50.31 - $317.72
Q1 2025	5,408	$205	$62.45	$30.01 - $91.83
Q4 2024	3,227	$248	$72.36	$55.33 - $86.93