PRAXIS PRECISION MEDICINES I

Ticker: PRAX CUSIP: 74006W207 Class: Common Stock

CHARLES SCHWAB INVESTMENT MANAGEMENT INC's Holding History (CIK: 0000884546)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 198,301 Value ($000) $58,447 Avg Close $186.22 Range $50.31 - $317.72

Q3 2025

Shares 161,661 Value ($000) $8,568 Avg Close $48.49 Range $37.19 - $61.03

Q2 2025

Shares 152,444 Value ($000) $6,410 Avg Close $38.08 Range $26.70 - $46.93

Q1 2025

Shares 141,080 Value ($000) $5,343 Avg Close $62.45 Range $30.01 - $91.83

Q4 2024

Shares 142,892 Value ($000) $10,997 Avg Close $72.36 Range $55.33 - $86.93

Q3 2024

Shares 137,052 Value ($000) $7,886 Avg Close $54.02 Range $38.99 - $63.93

Q2 2024

Shares 47,474 Value ($000) $1,964 Avg Close $47.26 Range $33.01 - $63.00

Q1 2024

Shares 6,689 Value ($000) $408 Avg Close $44.86 Range $20.50 - $67.21

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	198,301	$58,447	$186.22	$50.31 - $317.72
Q3 2025	161,661	$8,568	$48.49	$37.19 - $61.03
Q2 2025	152,444	$6,410	$38.08	$26.70 - $46.93
Q1 2025	141,080	$5,343	$62.45	$30.01 - $91.83
Q4 2024	142,892	$10,997	$72.36	$55.33 - $86.93
Q3 2024	137,052	$7,886	$54.02	$38.99 - $63.93
Q2 2024	47,474	$1,964	$47.26	$33.01 - $63.00
Q1 2024	6,689	$408	$44.86	$20.50 - $67.21