PRAXIS PRECISION MEDICINES I

Ticker: PRAX CUSIP: 74006W207 Class: Common Stock

MORGAN STANLEY's Holding History (CIK: 0000895421)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 889,889 Value ($000) $262,286 Avg Close $186.22 Range $50.31 - $317.72

Q3 2025

Shares 643,495 Value ($000) $34,105 Avg Close $48.49 Range $37.19 - $61.03

Q2 2025

Shares 1,226,339 Value ($000) $51,568 Avg Close $38.08 Range $26.70 - $46.93

Q1 2025

Shares 1,213,669 Value ($000) $45,962 Avg Close $62.45 Range $30.01 - $91.83

Q4 2024

Shares 1,163,526 Value ($000) $89,545 Avg Close $72.36 Range $55.33 - $86.93

Q3 2024

Shares 80,500 Value ($000) $4,632 Avg Close $54.02 Range $38.99 - $63.93

Q2 2024

Shares 184,319 Value ($000) $7,623 Avg Close $47.26 Range $33.01 - $63.00

Q1 2024

Shares 100,136 Value ($000) $6,110 Avg Close $44.86 Range $20.50 - $67.21

Q4 2023

Shares 16,933 Value ($000) $377 Avg Close $18.01 Range $13.01 - $27.60

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	889,889	$262,286	$186.22	$50.31 - $317.72
Q3 2025	643,495	$34,105	$48.49	$37.19 - $61.03
Q2 2025	1,226,339	$51,568	$38.08	$26.70 - $46.93
Q1 2025	1,213,669	$45,962	$62.45	$30.01 - $91.83
Q4 2024	1,163,526	$89,545	$72.36	$55.33 - $86.93
Q3 2024	80,500	$4,632	$54.02	$38.99 - $63.93
Q2 2024	184,319	$7,623	$47.26	$33.01 - $63.00
Q1 2024	100,136	$6,110	$44.86	$20.50 - $67.21
Q4 2023	16,933	$377	$18.01	$13.01 - $27.60