PRAXIS PRECISION MEDICINES I

Ticker: PRAX CUSIP: 74006W207 Class: Common Stock

MASSACHUSETTS FINANCIAL SERVICES CO /MA/'s Holding History (CIK: 0000912938)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 3,316 Value ($000) $977 Avg Close $186.22 Range $50.31 - $317.72

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	3,316	$977	$186.22	$50.31 - $317.72