PRAXIS PRECISION MEDICINES I

Ticker: PRAX CUSIP: 74006W207 Class: Common Stock

Invesco Ltd.'s Holding History (CIK: 0000914208)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 77,088 Value ($000) $22,721 Avg Close $186.22 Range $50.31 - $317.72

Q3 2025

Shares 20,868 Value ($000) $1,106 Avg Close $48.49 Range $37.19 - $61.03

Q2 2025

Shares 15,939 Value ($000) $670 Avg Close $38.08 Range $26.70 - $46.93

Q1 2025

Shares 11,678 Value ($000) $442 Avg Close $62.45 Range $30.01 - $91.83

Q4 2024

Shares 86,983 Value ($000) $6,694 Avg Close $72.36 Range $55.33 - $86.93

Q3 2024

Shares 107,713 Value ($000) $6,198 Avg Close $54.02 Range $38.99 - $63.93

Q2 2024

Shares 8,812 Value ($000) $364 Avg Close $47.26 Range $33.01 - $63.00

Q1 2024

Shares 95,181 Value ($000) $5,808 Avg Close $44.86 Range $20.50 - $67.21

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	77,088	$22,721	$186.22	$50.31 - $317.72
Q3 2025	20,868	$1,106	$48.49	$37.19 - $61.03
Q2 2025	15,939	$670	$38.08	$26.70 - $46.93
Q1 2025	11,678	$442	$62.45	$30.01 - $91.83
Q4 2024	86,983	$6,694	$72.36	$55.33 - $86.93
Q3 2024	107,713	$6,198	$54.02	$38.99 - $63.93
Q2 2024	8,812	$364	$47.26	$33.01 - $63.00
Q1 2024	95,181	$5,808	$44.86	$20.50 - $67.21