PRAXIS PRECISION MEDICINES I

Ticker: PRAX CUSIP: 74006W207 Class: Common Stock

NISA INVESTMENT ADVISORS, LLC's Holding History (CIK: 0000937615)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 7,770 Value ($000) $2,290 Avg Close $186.22 Range $50.31 - $317.72

Q3 2025

Shares 7,129 Value ($000) $378 Avg Close $48.49 Range $37.19 - $61.03

Q2 2025

Shares 629 Value ($000) $26 Avg Close $38.08 Range $26.70 - $46.93

Q1 2025

Shares 334 Value ($000) $13 Avg Close $62.45 Range $30.01 - $91.83

Q4 2024

Shares 71 Value ($000) $5 Avg Close $72.36 Range $55.33 - $86.93

Q3 2024

Shares 58 Value ($000) $3 Avg Close $54.02 Range $38.99 - $63.93

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	7,770	$2,290	$186.22	$50.31 - $317.72
Q3 2025	7,129	$378	$48.49	$37.19 - $61.03
Q2 2025	629	$26	$38.08	$26.70 - $46.93
Q1 2025	334	$13	$62.45	$30.01 - $91.83
Q4 2024	71	$5	$72.36	$55.33 - $86.93
Q3 2024	58	$3	$54.02	$38.99 - $63.93