PRAXIS PRECISION MEDICINES I

Ticker: PRAX CUSIP: 74006W207 Class: Common Stock

CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM's Holding History (CIK: 0001081019)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 19,671 Value ($000) $5,798 Avg Close $186.22 Range $50.31 - $317.72

Q3 2025

Shares 18,583 Value ($000) $985 Avg Close $48.49 Range $37.19 - $61.03

Q2 2025

Shares 16,346 Value ($000) $687 Avg Close $38.08 Range $26.70 - $46.93

Q1 2025

Shares 16,346 Value ($000) $619 Avg Close $62.45 Range $30.01 - $91.83

Q4 2024

Shares 12,726 Value ($000) $979 Avg Close $72.36 Range $55.33 - $86.93

Q3 2024

Shares 12,451 Value ($000) $716 Avg Close $54.02 Range $38.99 - $63.93

Q2 2024

Shares 15,945 Value ($000) $659 Avg Close $47.26 Range $33.01 - $63.00

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	19,671	$5,798	$186.22	$50.31 - $317.72
Q3 2025	18,583	$985	$48.49	$37.19 - $61.03
Q2 2025	16,346	$687	$38.08	$26.70 - $46.93
Q1 2025	16,346	$619	$62.45	$30.01 - $91.83
Q4 2024	12,726	$979	$72.36	$55.33 - $86.93
Q3 2024	12,451	$716	$54.02	$38.99 - $63.93
Q2 2024	15,945	$659	$47.26	$33.01 - $63.00