PRAXIS PRECISION MEDICINES I

Ticker: PRAX CUSIP: 74006W207 Class: Common Stock

FIRST TRUST ADVISORS LP's Holding History (CIK: 0001125816)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 88,704 Value ($000) $26,145 Avg Close $186.22 Range $50.31 - $317.72

Q3 2025

Shares 28,966 Value ($000) $1,535 Avg Close $48.49 Range $37.19 - $61.03

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	88,704	$26,145	$186.22	$50.31 - $317.72
Q3 2025	28,966	$1,535	$48.49	$37.19 - $61.03