PRAXIS PRECISION MEDICINES I

Ticker: PRAX CUSIP: 74006W207 Class: Common Stock

HighVista Strategies LLC's Holding History (CIK: 0001335325)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 25,841 Value ($000) $7,616 Avg Close $186.22 Range $50.31 - $317.72

Q3 2025

Shares 95,002 Value ($000) $5,035 Avg Close $48.49 Range $37.19 - $61.03

Q2 2025

Shares 67,288 Value ($000) $2,829 Avg Close $38.08 Range $26.70 - $46.93

Q1 2025

Shares 39,286 Value ($000) $1,488 Avg Close $62.45 Range $30.01 - $91.83

Q4 2024

Shares 10,951 Value ($000) $843 Avg Close $72.36 Range $55.33 - $86.93

Q3 2024

Shares 10,951 Value ($000) $630 Avg Close $54.02 Range $38.99 - $63.93

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	25,841	$7,616	$186.22	$50.31 - $317.72
Q3 2025	95,002	$5,035	$48.49	$37.19 - $61.03
Q2 2025	67,288	$2,829	$38.08	$26.70 - $46.93
Q1 2025	39,286	$1,488	$62.45	$30.01 - $91.83
Q4 2024	10,951	$843	$72.36	$55.33 - $86.93
Q3 2024	10,951	$630	$54.02	$38.99 - $63.93