PRAXIS PRECISION MEDICINES I

Ticker: PRAX CUSIP: 74006W207 Class: Common Stock

PRELUDE CAPITAL MANAGEMENT, LLC's Holding History (CIK: 0001387508)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 16,038 Value ($000) $4,727 Avg Close $186.22 Range $50.31 - $317.72

Q3 2025

Shares 28,102 Value ($000) $1,489 Avg Close $48.49 Range $37.19 - $61.03

Q2 2025

Shares 19,900 Value ($000) $837 Avg Close $38.08 Range $26.70 - $46.93

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	16,038	$4,727	$186.22	$50.31 - $317.72
Q3 2025	28,102	$1,489	$48.49	$37.19 - $61.03
Q2 2025	19,900	$837	$38.08	$26.70 - $46.93