PRAXIS PRECISION MEDICINES I

Ticker: PRAX CUSIP: 74006W207 Class: Common Stock

MetLife Investment Management, LLC's Holding History (CIK: 0001529735)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 12,424 Value ($000) $3,662 Avg Close $186.22 Range $50.31 - $317.72

Q3 2025

Shares 10,520 Value ($000) $558 Avg Close $48.49 Range $37.19 - $61.03

Q2 2025

Shares 10,520 Value ($000) $442 Avg Close $38.08 Range $26.70 - $46.93

Q1 2025

Shares 10,597 Value ($000) $401 Avg Close $62.45 Range $30.01 - $91.83

Q4 2024

Shares 10,675 Value ($000) $822 Avg Close $72.36 Range $55.33 - $86.93

Q3 2024

Shares 10,131 Value ($000) $583 Avg Close $54.02 Range $38.99 - $63.93

Q2 2024

Shares 4,423 Value ($000) $183 Avg Close $47.26 Range $33.01 - $63.00

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	12,424	$3,662	$186.22	$50.31 - $317.72
Q3 2025	10,520	$558	$48.49	$37.19 - $61.03
Q2 2025	10,520	$442	$38.08	$26.70 - $46.93
Q1 2025	10,597	$401	$62.45	$30.01 - $91.83
Q4 2024	10,675	$822	$72.36	$55.33 - $86.93
Q3 2024	10,131	$583	$54.02	$38.99 - $63.93
Q2 2024	4,423	$183	$47.26	$33.01 - $63.00