PRAXIS PRECISION MEDICINES I

Ticker: PRAX CUSIP: 74006W207 Class: Common Stock

Candriam S.C.A.'s Holding History (CIK: 0001537014)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 110,590 Value ($000) $32,597 Avg Close $186.22 Range $50.31 - $317.72

Q3 2025

Shares 62,866 Value ($000) $3,332 Avg Close $48.49 Range $37.19 - $61.03

Q2 2025

Shares 63,671 Value ($000) $2,677 Avg Close $38.08 Range $26.70 - $46.93

Q1 2025

Shares 63,671 Value ($000) $2,411 Avg Close $62.45 Range $30.01 - $91.83

Q4 2024

Shares 117,970 Value ($000) $9,079 Avg Close $72.36 Range $55.33 - $86.93

Q3 2024

Shares 162,031 Value ($000) $9,323 Avg Close $54.02 Range $38.99 - $63.93

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	110,590	$32,597	$186.22	$50.31 - $317.72
Q3 2025	62,866	$3,332	$48.49	$37.19 - $61.03
Q2 2025	63,671	$2,677	$38.08	$26.70 - $46.93
Q1 2025	63,671	$2,411	$62.45	$30.01 - $91.83
Q4 2024	117,970	$9,079	$72.36	$55.33 - $86.93
Q3 2024	162,031	$9,323	$54.02	$38.99 - $63.93