PRAXIS PRECISION MEDICINES I

Ticker: PRAX CUSIP: 74006W207 Class: Common Stock

Assenagon Asset Management S.A.'s Holding History (CIK: 0001546007)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 408,787 Value ($000) $120,486 Avg Close $186.22 Range $50.31 - $317.72

Q3 2025

Shares 409,779 Value ($000) $21,718 Avg Close $48.49 Range $37.19 - $61.03

Q2 2025

Shares 604,298 Value ($000) $25,411 Avg Close $38.08 Range $26.70 - $46.93

Q1 2025

Shares 507,400 Value ($000) $19,215 Avg Close $62.45 Range $30.01 - $91.83

Q4 2024

Shares 559,082 Value ($000) $43,027 Avg Close $72.36 Range $55.33 - $86.93

Q3 2024

Shares 10,096 Value ($000) $581 Avg Close $54.02 Range $38.99 - $63.93

Q2 2024

Shares 19,761 Value ($000) $817 Avg Close $47.26 Range $33.01 - $63.00

Q1 2024

Shares 71,253 Value ($000) $4,348 Avg Close $44.86 Range $20.50 - $67.21

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	408,787	$120,486	$186.22	$50.31 - $317.72
Q3 2025	409,779	$21,718	$48.49	$37.19 - $61.03
Q2 2025	604,298	$25,411	$38.08	$26.70 - $46.93
Q1 2025	507,400	$19,215	$62.45	$30.01 - $91.83
Q4 2024	559,082	$43,027	$72.36	$55.33 - $86.93
Q3 2024	10,096	$581	$54.02	$38.99 - $63.93
Q2 2024	19,761	$817	$47.26	$33.01 - $63.00
Q1 2024	71,253	$4,348	$44.86	$20.50 - $67.21