PRAXIS PRECISION MEDICINES I

Ticker: PRAX CUSIP: 74006W207 Class: Common Stock

Arizona State Retirement System's Holding History (CIK: 0001558481)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 5,723 Value ($000) $1,687 Avg Close $186.22 Range $50.31 - $317.72

Q3 2025

Shares 5,417 Value ($000) $287 Avg Close $48.49 Range $37.19 - $61.03

Q4 2024

Shares 3,851 Value ($000) $296 Avg Close $72.36 Range $55.33 - $86.93

Q3 2024

Shares 3,695 Value ($000) $213 Avg Close $54.02 Range $38.99 - $63.93

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	5,723	$1,687	$186.22	$50.31 - $317.72
Q3 2025	5,417	$287	$48.49	$37.19 - $61.03
Q4 2024	3,851	$296	$72.36	$55.33 - $86.93
Q3 2024	3,695	$213	$54.02	$38.99 - $63.93