PRAXIS PRECISION MEDICINES I

Ticker: PRAX CUSIP: 74006W207 Class: Common Stock

Swiss National Bank's Holding History (CIK: 0001582202)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 40,500 Value ($000) $11,937 Avg Close $186.22 Range $50.31 - $317.72

Q3 2025

Shares 35,500 Value ($000) $1,882 Avg Close $48.49 Range $37.19 - $61.03

Q2 2025

Shares 30,800 Value ($000) $1,295 Avg Close $38.08 Range $26.70 - $46.93

Q1 2025

Shares 27,100 Value ($000) $1,026 Avg Close $62.45 Range $30.01 - $91.83

Q4 2024

Shares 26,100 Value ($000) $2,009 Avg Close $72.36 Range $55.33 - $86.93

Q3 2024

Shares 25,100 Value ($000) $1,444 Avg Close $54.02 Range $38.99 - $63.93

Q2 2024

Shares 32,000 Value ($000) $1,324 Avg Close $47.26 Range $33.01 - $63.00

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	40,500	$11,937	$186.22	$50.31 - $317.72
Q3 2025	35,500	$1,882	$48.49	$37.19 - $61.03
Q2 2025	30,800	$1,295	$38.08	$26.70 - $46.93
Q1 2025	27,100	$1,026	$62.45	$30.01 - $91.83
Q4 2024	26,100	$2,009	$72.36	$55.33 - $86.93
Q3 2024	25,100	$1,444	$54.02	$38.99 - $63.93
Q2 2024	32,000	$1,324	$47.26	$33.01 - $63.00