PRAXIS PRECISION MEDICINES I

Ticker: PRAX CUSIP: 74006W207 Class: Common Stock

VR Adviser, LLC's Holding History (CIK: 0001615982)

Note: Option positions (PUT/CALL) are excluded.

Q1 2025

Shares 989,985 Value ($000) $37,491 Avg Close $62.45 Range $30.01 - $91.83

Q4 2024

Shares 989,985 Value ($000) $76,189 Avg Close $72.36 Range $55.33 - $86.93

Q3 2024

Shares 706,131 Value ($000) $40,631 Avg Close $54.02 Range $38.99 - $63.93

Q2 2024

Shares 706,131 Value ($000) $29,206 Avg Close $47.26 Range $33.01 - $63.00

Q1 2024

Shares 706,126 Value ($000) $43,088 Avg Close $44.86 Range $20.50 - $67.21

Q4 2023

Shares 353,626 Value ($000) $7,879 Avg Close $18.01 Range $13.01 - $27.60

Period	Shares	Value ($000)	Average Close	Price Range
Q1 2025	989,985	$37,491	$62.45	$30.01 - $91.83
Q4 2024	989,985	$76,189	$72.36	$55.33 - $86.93
Q3 2024	706,131	$40,631	$54.02	$38.99 - $63.93
Q2 2024	706,131	$29,206	$47.26	$33.01 - $63.00
Q1 2024	706,126	$43,088	$44.86	$20.50 - $67.21
Q4 2023	353,626	$7,879	$18.01	$13.01 - $27.60