PRAXIS PRECISION MEDICINES I

Ticker: PRAX CUSIP: 74006W207 Class: Common Stock

Man Group plc's Holding History (CIK: 0001637460)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 21,170 Value ($000) $6,240 Avg Close $186.22 Range $50.31 - $317.72

Q4 2024

Shares 2,832 Value ($000) $218 Avg Close $72.36 Range $55.33 - $86.93

Q3 2024

Shares 4,041 Value ($000) $233 Avg Close $54.02 Range $38.99 - $63.93

Q2 2024

Shares 6,658 Value ($000) $275 Avg Close $47.26 Range $33.01 - $63.00

Q1 2024

Shares 15,921 Value ($000) $971 Avg Close $44.86 Range $20.50 - $67.21

Q4 2023

Shares 13,139 Value ($000) $293 Avg Close $18.01 Range $13.01 - $27.60

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	21,170	$6,240	$186.22	$50.31 - $317.72
Q4 2024	2,832	$218	$72.36	$55.33 - $86.93
Q3 2024	4,041	$233	$54.02	$38.99 - $63.93
Q2 2024	6,658	$275	$47.26	$33.01 - $63.00
Q1 2024	15,921	$971	$44.86	$20.50 - $67.21
Q4 2023	13,139	$293	$18.01	$13.01 - $27.60