PRAXIS PRECISION MEDICINES I

Ticker: PRAX CUSIP: 74006W207 Class: Common Stock

Orbis Allan Gray Ltd's Holding History (CIK: 0001663865)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 1,255,162 Value ($000) $369,946 Avg Close $186.22 Range $50.31 - $317.72

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	1,255,162	$369,946	$186.22	$50.31 - $317.72