PRAXIS PRECISION MEDICINES I

Ticker: PRAX CUSIP: 74006W207 Class: Common Stock

Ikarian Capital, LLC's Holding History (CIK: 0001778253)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 86,581 Value ($000) $25,519 Avg Close $186.22 Range $50.31 - $317.72

Q3 2025

Shares 28,571 Value ($000) $1,514 Avg Close $48.49 Range $37.19 - $61.03

Q2 2025

Shares 276,950 Value ($000) $11,646 Avg Close $38.08 Range $26.70 - $46.93

Q1 2025

Shares 145,502 Value ($000) $5,510 Avg Close $62.45 Range $30.01 - $91.83

Q1 2024

Shares 168,388 Value ($000) $10,275 Avg Close $44.86 Range $20.50 - $67.21

Q4 2023

Shares 200,000 Value ($000) $4,456 Avg Close $18.01 Range $13.01 - $27.60

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	86,581	$25,519	$186.22	$50.31 - $317.72
Q3 2025	28,571	$1,514	$48.49	$37.19 - $61.03
Q2 2025	276,950	$11,646	$38.08	$26.70 - $46.93
Q1 2025	145,502	$5,510	$62.45	$30.01 - $91.83
Q1 2024	168,388	$10,275	$44.86	$20.50 - $67.21
Q4 2023	200,000	$4,456	$18.01	$13.01 - $27.60