PRAXIS PRECISION MEDICINES I

Ticker: PRAX CUSIP: 74006W207 Class: Common Stock

5AM Venture Management, LLC's Holding History (CIK: 0001799883)

Note: Option positions (PUT/CALL) are excluded.

Q3 2025
Shares 170,000 Value ($000) $9,010 Avg Close $48.49 Range $37.19 - $61.03
Q2 2025
Shares 170,000 Value ($000) $7,149 Avg Close $38.08 Range $26.70 - $46.93
Q1 2025
Shares 170,000 Value ($000) $6,438 Avg Close $62.45 Range $30.01 - $91.83
Q4 2024
Shares 170,000 Value ($000) $13,083 Avg Close $72.36 Range $55.33 - $86.93
Q3 2024
Shares 340,000 Value ($000) $19,564 Avg Close $54.02 Range $38.99 - $63.93
Q2 2024
Shares 340,000 Value ($000) $14,062 Avg Close $47.26 Range $33.01 - $63.00
Q1 2024
Shares 340,000 Value ($000) $20,747 Avg Close $44.86 Range $20.50 - $67.21