PRAXIS PRECISION MEDICINES I

Ticker: PRAX CUSIP: 74006W207 Class: Common Stock

Tri Locum Partners LP's Holding History (CIK: 0001826434)

Note: Option positions (PUT/CALL) are excluded.

Q3 2025

Shares 75,986 Value ($000) $4,027 Avg Close $48.49 Range $37.19 - $61.03

Q2 2025

Shares 195,432 Value ($000) $8,218 Avg Close $38.08 Range $26.70 - $46.93

Q1 2025

Shares 83,659 Value ($000) $3,168 Avg Close $62.45 Range $30.01 - $91.83

Q4 2024

Shares 37,269 Value ($000) $2,868 Avg Close $72.36 Range $55.33 - $86.93

Q2 2024

Shares 75,319 Value ($000) $3,115 Avg Close $47.26 Range $33.01 - $63.00

Q1 2024

Shares 106,494 Value ($000) $6,498 Avg Close $44.86 Range $20.50 - $67.21

Q4 2023

Shares 248,761 Value ($000) $5,542 Avg Close $18.01 Range $13.01 - $27.60

Period	Shares	Value ($000)	Average Close	Price Range
Q3 2025	75,986	$4,027	$48.49	$37.19 - $61.03
Q2 2025	195,432	$8,218	$38.08	$26.70 - $46.93
Q1 2025	83,659	$3,168	$62.45	$30.01 - $91.83
Q4 2024	37,269	$2,868	$72.36	$55.33 - $86.93
Q2 2024	75,319	$3,115	$47.26	$33.01 - $63.00
Q1 2024	106,494	$6,498	$44.86	$20.50 - $67.21
Q4 2023	248,761	$5,542	$18.01	$13.01 - $27.60