PRELUDE THERAPEUTICS INC

Ticker: PRLD CUSIP: 74065P101 Class: Common Stock

Point72 Asset Management, L.P.'s Holding History (CIK: 0001603466)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 59,168 Value ($000) $172 Avg Close $1.69 Range $1.15 - $4.22

Q1 2023

Shares 1,222 Value ($000) $7 Avg Close $6.10 Range $4.42 - $7.65

Q3 2020

Shares 155,690 Value ($000) $4,691 Avg Close $28.24 Range $23.69 - $31.44

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	59,168	$172	$1.69	$1.15 - $4.22
Q1 2023	1,222	$7	$6.10	$4.42 - $7.65
Q3 2020	155,690	$4,691	$28.24	$23.69 - $31.44