PRELUDE THERAPEUTICS INC

Ticker: PRLD CUSIP: 74065P101 Class: Common Stock

Qube Research & Technologies Ltd's Holding History (CIK: 0001729829)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 21,551 Value ($000) $62 Avg Close $1.69 Range $1.15 - $4.22

Q2 2024

Shares 3,126 Value ($000) $12 Avg Close $4.07 Range $3.32 - $5.83

Q1 2023

Shares 30,377 Value ($000) $173 Avg Close $6.10 Range $4.42 - $7.65

Q4 2022

Shares 13,127 Value ($000) $79 Avg Close $6.41 Range $4.49 - $8.66

Q4 2021

Shares 23,384 Value ($000) $291 Avg Close $16.27 Range $10.96 - $32.77

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	21,551	$62	$1.69	$1.15 - $4.22
Q2 2024	3,126	$12	$4.07	$3.32 - $5.83
Q1 2023	30,377	$173	$6.10	$4.42 - $7.65
Q4 2022	13,127	$79	$6.41	$4.49 - $8.66
Q4 2021	23,384	$291	$16.27	$10.96 - $32.77