PROTALIX BIOTHERAPEUTICS INC

CUSIP: 74365A101 Class: COM

Opaleye Management Inc.'s Holding History (CIK: 0001595855)

Note: Option positions (PUT/CALL) are excluded.

Q2 2019
Shares 1,000,000 Value ($000) $469 Avg Close — Range —
Q4 2018
Shares 2,500,000 Value ($000) $777 Avg Close — Range —
Q3 2018
Shares 2,500,000 Value ($000) $1,817 Avg Close — Range —
Q2 2018
Shares 3,100,000 Value ($000) $1,333 Avg Close — Range —
Q1 2018
Shares 3,260,000 Value ($000) $1,760 Avg Close — Range —
Q4 2017
Shares 1,825,000 Value ($000) $1,206 Avg Close — Range —