PROTALIX BIOTHERAPEUTICS INC

CUSIP: 74365AAB7 Class: CONV BONDS

Opaleye Management Inc.'s Holding History (CIK: 0001595855)

Note: Option positions (PUT/CALL) are excluded.

Q2 2017
Shares 1,835,000 Value ($000) $1,537 Avg Close — Range —
Q1 2017
Shares 1,930,000 Value ($000) $2,624 Avg Close — Range —
Q4 2016
Shares 1,930,000 Value ($000) $859 Avg Close — Range —
Q3 2016
Shares 8,070,000 Value ($000) $4,600 Avg Close — Range —
Q2 2016
Shares 8,200,000 Value ($000) $5,248 Avg Close — Range —
Q1 2016
Shares 8,200,000 Value ($000) $6,892 Avg Close — Range —
Q4 2015
Shares 8,100,000 Value ($000) $8,262 Avg Close — Range —
Q3 2015
Shares 3,640,000 Value ($000) $4,295 Avg Close — Range —
Q2 2015
Shares 2,505,000 Value ($000) $4,885 Avg Close — Range —