PROTAGONIST THERAPEUTICS INC

Ticker: PTGX CUSIP: 74366E102 Class: Common Stock

BROWN BROTHERS HARRIMAN & CO's Holding History (CIK: 0000014661)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 81 Value ($000) $7 Avg Close $81.85 Range $62.24 - $96.54

Q3 2025

Shares 81 Value ($000) $5 Avg Close $56.84 Range $49.38 - $68.26

Q2 2025

Shares 81 Value ($000) $4 Avg Close $47.99 Range $39.60 - $57.70

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	81	$7	$81.85	$62.24 - $96.54
Q3 2025	81	$5	$56.84	$49.38 - $68.26
Q2 2025	81	$4	$47.99	$39.60 - $57.70