PROTAGONIST THERAPEUTICS INC

Ticker: PTGX CUSIP: 74366E102 Class: Common Stock

JENNISON ASSOCIATES LLC's Holding History (CIK: 0000053417)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 331,164 Value ($000) $28,924 Avg Close $81.85 Range $62.24 - $96.54

Q1 2025

Shares 18,317 Value ($000) $886 Avg Close $41.90 Range $33.70 - $60.60

Q1 2023

Shares 428,938 Value ($000) $9,866 Avg Close $16.79 Range $10.62 - $25.69

Q3 2018

Shares 349,697 Value ($000) $3,598 Avg Close $8.61 Range $6.57 - $11.90

Q4 2017

Shares 100,000 Value ($000) $2,080 Avg Close $17.74 Range $14.10 - $21.31

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	331,164	$28,924	$81.85	$62.24 - $96.54
Q1 2025	18,317	$886	$41.90	$33.70 - $60.60
Q1 2023	428,938	$9,866	$16.79	$10.62 - $25.69
Q3 2018	349,697	$3,598	$8.61	$6.57 - $11.90
Q4 2017	100,000	$2,080	$17.74	$14.10 - $21.31