PROTAGONIST THERAPEUTICS INC

Ticker: PTGX CUSIP: 74366E102 Class: Common Stock

FIRST MANHATTAN CO. LLC.'s Holding History (CIK: 0000728083)

Note: Option positions (PUT/CALL) are excluded.

Q2 2022

Shares 55,800 Value ($000) $441 Avg Close $12.09 Range $6.91 - $25.76

Q2 2018

Shares 128,244 Value ($000) $861 Avg Close $7.68 Range $5.50 - $9.44

Q1 2018

Shares 144,444 Value ($000) $1,240 Avg Close $18.83 Range $7.85 - $23.97

Q4 2017

Shares 416,364 Value ($000) $8,660 Avg Close $17.74 Range $14.10 - $21.31

Q3 2017

Shares 16,600 Value ($000) $293 Avg Close $13.85 Range $10.26 - $18.37

Period	Shares	Value ($000)	Average Close	Price Range
Q2 2022	55,800	$441	$12.09	$6.91 - $25.76
Q2 2018	128,244	$861	$7.68	$5.50 - $9.44
Q1 2018	144,444	$1,240	$18.83	$7.85 - $23.97
Q4 2017	416,364	$8,660	$17.74	$14.10 - $21.31
Q3 2017	16,600	$293	$13.85	$10.26 - $18.37