PROTAGONIST THERAPEUTICS INC

Ticker: PTGX CUSIP: 74366E102 Class: Common Stock

Invesco Ltd.'s Holding History (CIK: 0000914208)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 1,567,840 Value ($000) $136,935 Avg Close $81.85 Range $62.24 - $96.54

Q3 2025

Shares 1,003,706 Value ($000) $66,676 Avg Close $56.84 Range $49.38 - $68.26

Q2 2025

Shares 721,680 Value ($000) $39,887 Avg Close $47.99 Range $39.60 - $57.70

Q1 2025

Shares 859,648 Value ($000) $41,573 Avg Close $41.90 Range $33.70 - $60.60

Q4 2024

Shares 738,952 Value ($000) $28,524 Avg Close $43.60 Range $33.31 - $48.89

Q3 2024

Shares 653,152 Value ($000) $29,392 Avg Close $40.40 Range $32.50 - $48.00

Q2 2024

Shares 88,434 Value ($000) $3,064 Avg Close $29.29 Range $24.22 - $35.96

Q1 2024

Shares 28,359 Value ($000) $820 Avg Close $27.21 Range $21.43 - $33.34

Q4 2023

Shares 45,763 Value ($000) $1,049 Avg Close $17.50 Range $13.72 - $23.88

Q3 2023

Shares 40,901 Value ($000) $682 Avg Close $19.40 Range $16.33 - $26.81

Q2 2023

Shares 264,411 Value ($000) $7,303 Avg Close $25.03 Range $17.64 - $30.10

Q1 2023

Shares 277,936 Value ($000) $6,393 Avg Close $16.79 Range $10.62 - $25.69

Q4 2022

Shares 31,552 Value ($000) $344 Avg Close $8.44 Range $7.24 - $11.46

Q3 2022

Shares 28,724 Value ($000) $242 Avg Close $9.46 Range $7.68 - $11.97

Q2 2022

Shares 29,503 Value ($000) $233 Avg Close $12.09 Range $6.91 - $25.76

Q1 2022

Shares 30,026 Value ($000) $711 Avg Close $28.17 Range $22.56 - $37.05

Q4 2021

Shares 19,825 Value ($000) $678 Avg Close $31.61 Range $17.26 - $38.11

Q3 2021

Shares 22,452 Value ($000) $398 Avg Close $42.63 Range $12.80 - $50.54

Q2 2021

Shares 18,122 Value ($000) $814 Avg Close $33.01 Range $24.14 - $45.93

Q1 2021

Shares 10,103 Value ($000) $262 Avg Close $25.31 Range $18.82 - $32.10

Q3 2020

Shares 189,232 Value ($000) $3,699 Avg Close $18.76 Range $14.16 - $23.25

Q2 2020

Shares 234,281 Value ($000) $4,137 Avg Close $12.55 Range $6.00 - $19.67

Q1 2020

Shares 84,930 Value ($000) $599 Avg Close $7.49 Range $5.30 - $9.30

Q3 2019

Shares 63,653 Value ($000) $764 Avg Close $12.60 Range $8.26 - $16.67

Q2 2019

Shares 84,849 Value ($000) $1,028 Avg Close $11.06 Range $8.88 - $13.14

Q1 2019

Shares 71,313 Value ($000) $896 Avg Close $8.83 Range $6.38 - $14.36

Q2 2018

Shares 72,964 Value ($000) $490 Avg Close $7.68 Range $5.50 - $9.44

Q1 2018

Shares 56,308 Value ($000) $484 Avg Close $18.83 Range $7.85 - $23.97

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	1,567,840	$136,935	$81.85	$62.24 - $96.54
Q3 2025	1,003,706	$66,676	$56.84	$49.38 - $68.26
Q2 2025	721,680	$39,887	$47.99	$39.60 - $57.70
Q1 2025	859,648	$41,573	$41.90	$33.70 - $60.60
Q4 2024	738,952	$28,524	$43.60	$33.31 - $48.89
Q3 2024	653,152	$29,392	$40.40	$32.50 - $48.00
Q2 2024	88,434	$3,064	$29.29	$24.22 - $35.96
Q1 2024	28,359	$820	$27.21	$21.43 - $33.34
Q4 2023	45,763	$1,049	$17.50	$13.72 - $23.88
Q3 2023	40,901	$682	$19.40	$16.33 - $26.81
Q2 2023	264,411	$7,303	$25.03	$17.64 - $30.10
Q1 2023	277,936	$6,393	$16.79	$10.62 - $25.69
Q4 2022	31,552	$344	$8.44	$7.24 - $11.46
Q3 2022	28,724	$242	$9.46	$7.68 - $11.97
Q2 2022	29,503	$233	$12.09	$6.91 - $25.76
Q1 2022	30,026	$711	$28.17	$22.56 - $37.05
Q4 2021	19,825	$678	$31.61	$17.26 - $38.11
Q3 2021	22,452	$398	$42.63	$12.80 - $50.54
Q2 2021	18,122	$814	$33.01	$24.14 - $45.93
Q1 2021	10,103	$262	$25.31	$18.82 - $32.10
Q3 2020	189,232	$3,699	$18.76	$14.16 - $23.25
Q2 2020	234,281	$4,137	$12.55	$6.00 - $19.67
Q1 2020	84,930	$599	$7.49	$5.30 - $9.30
Q3 2019	63,653	$764	$12.60	$8.26 - $16.67
Q2 2019	84,849	$1,028	$11.06	$8.88 - $13.14
Q1 2019	71,313	$896	$8.83	$6.38 - $14.36
Q2 2018	72,964	$490	$7.68	$5.50 - $9.44
Q1 2018	56,308	$484	$18.83	$7.85 - $23.97