PROTAGONIST THERAPEUTICS INC

Ticker: PTGX CUSIP: 74366E102 Class: Common Stock

CAPITAL FUND MANAGEMENT S.A.'s Holding History (CIK: 0001323645)

Note: Option positions (PUT/CALL) are excluded.

Q3 2025

Shares 20,348 Value ($000) $1,352 Avg Close $56.84 Range $49.38 - $68.26

Q2 2025

Shares 49,805 Value ($000) $2,753 Avg Close $47.99 Range $39.60 - $57.70

Q4 2024

Shares 28,058 Value ($000) $1,083 Avg Close $43.60 Range $33.31 - $48.89

Q3 2023

Shares 12,629 Value ($000) $211 Avg Close $19.40 Range $16.33 - $26.81

Q2 2023

Shares 26,605 Value ($000) $735 Avg Close $25.03 Range $17.64 - $30.10

Q2 2022

Shares 116,807 Value ($000) $923,943 Avg Close $12.09 Range $6.91 - $25.76

Period	Shares	Value ($000)	Average Close	Price Range
Q3 2025	20,348	$1,352	$56.84	$49.38 - $68.26
Q2 2025	49,805	$2,753	$47.99	$39.60 - $57.70
Q4 2024	28,058	$1,083	$43.60	$33.31 - $48.89
Q3 2023	12,629	$211	$19.40	$16.33 - $26.81
Q2 2023	26,605	$735	$25.03	$17.64 - $30.10
Q2 2022	116,807	$923,943	$12.09	$6.91 - $25.76