PROTAGONIST THERAPEUTICS INC

Ticker: PTGX CUSIP: 74366E102 Class: Common Stock

RA CAPITAL MANAGEMENT, L.P.'s Holding History (CIK: 0001346824)

Note: Option positions (PUT/CALL) are excluded.

Q1 2017

Shares 636,248 Value ($000) $8,150 Avg Close $16.11 Range $12.10 - $22.50

Q4 2016

Shares 692,563 Value ($000) $14,634 Avg Close $22.30 Range $17.45 - $26.36

Q3 2016

Shares 754,411 Value ($000) $15,941 Avg Close $13.67 Range $10.02 - $22.56

Period	Shares	Value ($000)	Average Close	Price Range
Q1 2017	636,248	$8,150	$16.11	$12.10 - $22.50
Q4 2016	692,563	$14,634	$22.30	$17.45 - $26.36
Q3 2016	754,411	$15,941	$13.67	$10.02 - $22.56