PROTAGONIST THERAPEUTICS INC

Ticker: PTGX CUSIP: 74366E102 Class: Common Stock

CITADEL ADVISORS LLC's Holding History (CIK: 0001423053)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 1,126,687 Value ($000) $98,405 Avg Close $81.85 Range $62.24 - $96.54

Q3 2025

Shares 237,881 Value ($000) $15,802 Avg Close $56.84 Range $49.38 - $68.26

Q2 2025

Shares 27,201 Value ($000) $1,503 Avg Close $47.99 Range $39.60 - $57.70

Q1 2025

Shares 154,067 Value ($000) $7,451 Avg Close $41.90 Range $33.70 - $60.60

Q4 2024

Shares 164,146 Value ($000) $6,336 Avg Close $43.60 Range $33.31 - $48.89

Q3 2024

Shares 5,030 Value ($000) $226 Avg Close $40.40 Range $32.50 - $48.00

Q1 2024

Shares 45,616 Value ($000) $1,320 Avg Close $27.21 Range $21.43 - $33.34

Q4 2023

Shares 47,864 Value ($000) $1,098 Avg Close $17.50 Range $13.72 - $23.88

Q3 2023

Shares 50,796 Value ($000) $847 Avg Close $19.40 Range $16.33 - $26.81

Q2 2023

Shares 548,994 Value ($000) $15,163 Avg Close $25.03 Range $17.64 - $30.10

Q1 2023

Shares 1,164,680 Value ($000) $26,788 Avg Close $16.79 Range $10.62 - $25.69

Q4 2022

Shares 2,355,314 Value ($000) $25,696 Avg Close $8.44 Range $7.24 - $11.46

Q3 2022

Shares 866,387 Value ($000) $7,304 Avg Close $9.46 Range $7.68 - $11.97

Q2 2022

Shares 74,129 Value ($000) $586 Avg Close $12.09 Range $6.91 - $25.76

Q1 2022

Shares 186,824 Value ($000) $4,424 Avg Close $28.17 Range $22.56 - $37.05

Q4 2021

Shares 35,548 Value ($000) $1,216 Avg Close $31.61 Range $17.26 - $38.11

Q3 2021

Shares 118,704 Value ($000) $2,104 Avg Close $42.63 Range $12.80 - $50.54

Q2 2021

Shares 403,208 Value ($000) $18,096 Avg Close $33.01 Range $24.14 - $45.93

Q1 2021

Shares 198,218 Value ($000) $5,133 Avg Close $25.31 Range $18.82 - $32.10

Q4 2020

Shares 340,822 Value ($000) $6,871 Avg Close $21.52 Range $17.44 - $25.65

Q1 2020

Shares 469,212 Value ($000) $3,313 Avg Close $7.49 Range $5.30 - $9.30

Q4 2019

Shares 459,093 Value ($000) $3,236 Avg Close $9.93 Range $4.47 - $13.77

Q3 2019

Shares 416,255 Value ($000) $4,999 Avg Close $12.60 Range $8.26 - $16.67

Q2 2019

Shares 409,847 Value ($000) $4,963 Avg Close $11.06 Range $8.88 - $13.14

Q1 2019

Shares 363,727 Value ($000) $4,572 Avg Close $8.83 Range $6.38 - $14.36

Q4 2018

Shares 34,762 Value ($000) $234 Avg Close $7.93 Range $5.49 - $10.50

Q3 2018

Shares 35,757 Value ($000) $368 Avg Close $8.61 Range $6.57 - $11.90

Q2 2018

Shares 131,401 Value ($000) $883 Avg Close $7.68 Range $5.50 - $9.44

Q1 2018

Shares 49,197 Value ($000) $423 Avg Close $18.83 Range $7.85 - $23.97

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	1,126,687	$98,405	$81.85	$62.24 - $96.54
Q3 2025	237,881	$15,802	$56.84	$49.38 - $68.26
Q2 2025	27,201	$1,503	$47.99	$39.60 - $57.70
Q1 2025	154,067	$7,451	$41.90	$33.70 - $60.60
Q4 2024	164,146	$6,336	$43.60	$33.31 - $48.89
Q3 2024	5,030	$226	$40.40	$32.50 - $48.00
Q1 2024	45,616	$1,320	$27.21	$21.43 - $33.34
Q4 2023	47,864	$1,098	$17.50	$13.72 - $23.88
Q3 2023	50,796	$847	$19.40	$16.33 - $26.81
Q2 2023	548,994	$15,163	$25.03	$17.64 - $30.10
Q1 2023	1,164,680	$26,788	$16.79	$10.62 - $25.69
Q4 2022	2,355,314	$25,696	$8.44	$7.24 - $11.46
Q3 2022	866,387	$7,304	$9.46	$7.68 - $11.97
Q2 2022	74,129	$586	$12.09	$6.91 - $25.76
Q1 2022	186,824	$4,424	$28.17	$22.56 - $37.05
Q4 2021	35,548	$1,216	$31.61	$17.26 - $38.11
Q3 2021	118,704	$2,104	$42.63	$12.80 - $50.54
Q2 2021	403,208	$18,096	$33.01	$24.14 - $45.93
Q1 2021	198,218	$5,133	$25.31	$18.82 - $32.10
Q4 2020	340,822	$6,871	$21.52	$17.44 - $25.65
Q1 2020	469,212	$3,313	$7.49	$5.30 - $9.30
Q4 2019	459,093	$3,236	$9.93	$4.47 - $13.77
Q3 2019	416,255	$4,999	$12.60	$8.26 - $16.67
Q2 2019	409,847	$4,963	$11.06	$8.88 - $13.14
Q1 2019	363,727	$4,572	$8.83	$6.38 - $14.36
Q4 2018	34,762	$234	$7.93	$5.49 - $10.50
Q3 2018	35,757	$368	$8.61	$6.57 - $11.90
Q2 2018	131,401	$883	$7.68	$5.50 - $9.44
Q1 2018	49,197	$423	$18.83	$7.85 - $23.97