PROTAGONIST THERAPEUTICS INC

Ticker: PTGX CUSIP: 74366E102 Class: Common Stock

O'SHAUGHNESSY ASSET MANAGEMENT, LLC's Holding History (CIK: 0001423442)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 4,369 Value ($000) $382 Avg Close $81.85 Range $62.24 - $96.54

Q3 2024

Shares 4,551 Value ($000) $211 Avg Close $40.40 Range $32.50 - $48.00

Q3 2021

Shares 2,162 Value ($000) $38 Avg Close $42.63 Range $12.80 - $50.54

Q2 2021

Shares 2,403 Value ($000) $108 Avg Close $33.01 Range $24.14 - $45.93

Q1 2021

Shares 2,206 Value ($000) $57 Avg Close $25.31 Range $18.82 - $32.10

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	4,369	$382	$81.85	$62.24 - $96.54
Q3 2024	4,551	$211	$40.40	$32.50 - $48.00
Q3 2021	2,162	$38	$42.63	$12.80 - $50.54
Q2 2021	2,403	$108	$33.01	$24.14 - $45.93
Q1 2021	2,206	$57	$25.31	$18.82 - $32.10