PROTAGONIST THERAPEUTICS INC

Ticker: PTGX CUSIP: 74366E102 Class: Common Stock

SUSQUEHANNA INTERNATIONAL GROUP, LLP's Holding History (CIK: 0001446194)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 11,762 Value ($000) $1,027 Avg Close $81.85 Range $62.24 - $96.54

Q3 2025

Shares 63,188 Value ($000) $4,198 Avg Close $56.84 Range $49.38 - $68.26

Q2 2025

Shares 71,241 Value ($000) $3,937 Avg Close $47.99 Range $39.60 - $57.70

Q1 2025

Shares 192,239 Value ($000) $9,297 Avg Close $41.90 Range $33.70 - $60.60

Q4 2024

Shares 69,937 Value ($000) $2,700 Avg Close $43.60 Range $33.31 - $48.89

Q3 2024

Shares 40,357 Value ($000) $1,816 Avg Close $40.40 Range $32.50 - $48.00

Q2 2024

Shares 355,586 Value ($000) $12,321 Avg Close $29.29 Range $24.22 - $35.96

Q1 2024

Shares 71,818 Value ($000) $2,078 Avg Close $27.21 Range $21.43 - $33.34

Q4 2023

Shares 109,683 Value ($000) $2,515 Avg Close $17.50 Range $13.72 - $23.88

Q3 2023

Shares 57,245 Value ($000) $955 Avg Close $19.40 Range $16.33 - $26.81

Q2 2023

Shares 15,964 Value ($000) $441 Avg Close $25.03 Range $17.64 - $30.10

Q1 2023

Shares 124,084 Value ($000) $2,854 Avg Close $16.79 Range $10.62 - $25.69

Q4 2022

Shares 67,031 Value ($000) $731 Avg Close $8.44 Range $7.24 - $11.46

Q3 2022

Shares 146,488 Value ($000) $1,235 Avg Close $9.46 Range $7.68 - $11.97

Q2 2022

Shares 65,160 Value ($000) $516 Avg Close $12.09 Range $6.91 - $25.76

Q1 2022

Shares 50,754 Value ($000) $1,202 Avg Close $28.17 Range $22.56 - $37.05

Q4 2021

Shares 296,413 Value ($000) $10,137 Avg Close $31.61 Range $17.26 - $38.11

Q3 2021

Shares 267,383 Value ($000) $4,738 Avg Close $42.63 Range $12.80 - $50.54

Q2 2021

Shares 21,333 Value ($000) $957 Avg Close $33.01 Range $24.14 - $45.93

Q1 2021

Shares 34,134 Value ($000) $884 Avg Close $25.31 Range $18.82 - $32.10

Q4 2020

Shares 20,353 Value ($000) $410 Avg Close $21.52 Range $17.44 - $25.65

Q3 2020

Shares 11,220 Value ($000) $219 Avg Close $18.76 Range $14.16 - $23.25

Q1 2019

Shares 47,788 Value ($000) $601 Avg Close $8.83 Range $6.38 - $14.36

Q4 2018

Shares 15,208 Value ($000) $102 Avg Close $7.93 Range $5.49 - $10.50

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	11,762	$1,027	$81.85	$62.24 - $96.54
Q3 2025	63,188	$4,198	$56.84	$49.38 - $68.26
Q2 2025	71,241	$3,937	$47.99	$39.60 - $57.70
Q1 2025	192,239	$9,297	$41.90	$33.70 - $60.60
Q4 2024	69,937	$2,700	$43.60	$33.31 - $48.89
Q3 2024	40,357	$1,816	$40.40	$32.50 - $48.00
Q2 2024	355,586	$12,321	$29.29	$24.22 - $35.96
Q1 2024	71,818	$2,078	$27.21	$21.43 - $33.34
Q4 2023	109,683	$2,515	$17.50	$13.72 - $23.88
Q3 2023	57,245	$955	$19.40	$16.33 - $26.81
Q2 2023	15,964	$441	$25.03	$17.64 - $30.10
Q1 2023	124,084	$2,854	$16.79	$10.62 - $25.69
Q4 2022	67,031	$731	$8.44	$7.24 - $11.46
Q3 2022	146,488	$1,235	$9.46	$7.68 - $11.97
Q2 2022	65,160	$516	$12.09	$6.91 - $25.76
Q1 2022	50,754	$1,202	$28.17	$22.56 - $37.05
Q4 2021	296,413	$10,137	$31.61	$17.26 - $38.11
Q3 2021	267,383	$4,738	$42.63	$12.80 - $50.54
Q2 2021	21,333	$957	$33.01	$24.14 - $45.93
Q1 2021	34,134	$884	$25.31	$18.82 - $32.10
Q4 2020	20,353	$410	$21.52	$17.44 - $25.65
Q3 2020	11,220	$219	$18.76	$14.16 - $23.25
Q1 2019	47,788	$601	$8.83	$6.38 - $14.36
Q4 2018	15,208	$102	$7.93	$5.49 - $10.50