PROTAGONIST THERAPEUTICS INC

Ticker: PTGX CUSIP: 74366E102 Class: Common Stock

HighTower Advisors, LLC's Holding History (CIK: 0001462245)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 7,127 Value ($000) $622 Avg Close $81.85 Range $62.24 - $96.54

Q3 2025

Shares 8,613 Value ($000) $572 Avg Close $56.84 Range $49.38 - $68.26

Q2 2025

Shares 9,980 Value ($000) $552 Avg Close $47.99 Range $39.60 - $57.70

Q1 2025

Shares 6,518 Value ($000) $315 Avg Close $41.90 Range $33.70 - $60.60

Q3 2024

Shares 10,887 Value ($000) $487 Avg Close $40.40 Range $32.50 - $48.00

Q2 2024

Shares 23,784 Value ($000) $828 Avg Close $29.29 Range $24.22 - $35.96

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	7,127	$622	$81.85	$62.24 - $96.54
Q3 2025	8,613	$572	$56.84	$49.38 - $68.26
Q2 2025	9,980	$552	$47.99	$39.60 - $57.70
Q1 2025	6,518	$315	$41.90	$33.70 - $60.60
Q3 2024	10,887	$487	$40.40	$32.50 - $48.00
Q2 2024	23,784	$828	$29.29	$24.22 - $35.96