PROTAGONIST THERAPEUTICS INC

Ticker: PTGX CUSIP: 74366E102 Class: Common Stock

MetLife Investment Management, LLC's Holding History (CIK: 0001529735)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 32,440 Value ($000) $2,833 Avg Close $81.85 Range $62.24 - $96.54

Q3 2025

Shares 33,846 Value ($000) $2,248 Avg Close $56.84 Range $49.38 - $68.26

Q2 2025

Shares 34,770 Value ($000) $1,922 Avg Close $47.99 Range $39.60 - $57.70

Q1 2025

Shares 34,790 Value ($000) $1,682 Avg Close $41.90 Range $33.70 - $60.60

Q4 2024

Shares 35,798 Value ($000) $1,382 Avg Close $43.60 Range $33.31 - $48.89

Q3 2024

Shares 33,805 Value ($000) $1,521 Avg Close $40.40 Range $32.50 - $48.00

Q2 2024

Shares 33,805 Value ($000) $1,171 Avg Close $29.29 Range $24.22 - $35.96

Q1 2024

Shares 28,596 Value ($000) $827 Avg Close $27.21 Range $21.43 - $33.34

Q4 2023

Shares 28,596 Value ($000) $656 Avg Close $17.50 Range $13.72 - $23.88

Q3 2023

Shares 28,596 Value ($000) $477 Avg Close $19.40 Range $16.33 - $26.81

Q2 2023

Shares 28,596 Value ($000) $790 Avg Close $25.03 Range $17.64 - $30.10

Q1 2023

Shares 23,914 Value ($000) $550 Avg Close $16.79 Range $10.62 - $25.69

Q4 2022

Shares 23,914 Value ($000) $261 Avg Close $8.44 Range $7.24 - $11.46

Q3 2022

Shares 23,914 Value ($000) $202 Avg Close $9.46 Range $7.68 - $11.97

Q2 2022

Shares 23,914 Value ($000) $189 Avg Close $12.09 Range $6.91 - $25.76

Q1 2022

Shares 23,914 Value ($000) $566 Avg Close $28.17 Range $22.56 - $37.05

Q4 2021

Shares 15,088 Value ($000) $516 Avg Close $31.61 Range $17.26 - $38.11

Q3 2021

Shares 15,088 Value ($000) $267 Avg Close $42.63 Range $12.80 - $50.54

Q2 2021

Shares 15,088 Value ($000) $677 Avg Close $33.01 Range $24.14 - $45.93

Q1 2021

Shares 13,524 Value ($000) $350 Avg Close $25.31 Range $18.82 - $32.10

Q4 2020

Shares 13,524 Value ($000) $273 Avg Close $21.52 Range $17.44 - $25.65

Q3 2020

Shares 13,524 Value ($000) $264 Avg Close $18.76 Range $14.16 - $23.25

Q2 2020

Shares 10,796 Value ($000) $191 Avg Close $12.55 Range $6.00 - $19.67

Q3 2019

Shares 9,114 Value ($000) $109 Avg Close $12.60 Range $8.26 - $16.67

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	32,440	$2,833	$81.85	$62.24 - $96.54
Q3 2025	33,846	$2,248	$56.84	$49.38 - $68.26
Q2 2025	34,770	$1,922	$47.99	$39.60 - $57.70
Q1 2025	34,790	$1,682	$41.90	$33.70 - $60.60
Q4 2024	35,798	$1,382	$43.60	$33.31 - $48.89
Q3 2024	33,805	$1,521	$40.40	$32.50 - $48.00
Q2 2024	33,805	$1,171	$29.29	$24.22 - $35.96
Q1 2024	28,596	$827	$27.21	$21.43 - $33.34
Q4 2023	28,596	$656	$17.50	$13.72 - $23.88
Q3 2023	28,596	$477	$19.40	$16.33 - $26.81
Q2 2023	28,596	$790	$25.03	$17.64 - $30.10
Q1 2023	23,914	$550	$16.79	$10.62 - $25.69
Q4 2022	23,914	$261	$8.44	$7.24 - $11.46
Q3 2022	23,914	$202	$9.46	$7.68 - $11.97
Q2 2022	23,914	$189	$12.09	$6.91 - $25.76
Q1 2022	23,914	$566	$28.17	$22.56 - $37.05
Q4 2021	15,088	$516	$31.61	$17.26 - $38.11
Q3 2021	15,088	$267	$42.63	$12.80 - $50.54
Q2 2021	15,088	$677	$33.01	$24.14 - $45.93
Q1 2021	13,524	$350	$25.31	$18.82 - $32.10
Q4 2020	13,524	$273	$21.52	$17.44 - $25.65
Q3 2020	13,524	$264	$18.76	$14.16 - $23.25
Q2 2020	10,796	$191	$12.55	$6.00 - $19.67
Q3 2019	9,114	$109	$12.60	$8.26 - $16.67