PROTAGONIST THERAPEUTICS INC

Ticker: PTGX CUSIP: 74366E102 Class: Common Stock

Assenagon Asset Management S.A.'s Holding History (CIK: 0001546007)

Note: Option positions (PUT/CALL) are excluded.

Q3 2025

Shares 65,756 Value ($000) $4,368 Avg Close $56.84 Range $49.38 - $68.26

Q2 2025

Shares 91,875 Value ($000) $5,078 Avg Close $47.99 Range $39.60 - $57.70

Q1 2025

Shares 44,872 Value ($000) $2,170 Avg Close $41.90 Range $33.70 - $60.60

Q4 2024

Shares 52,239 Value ($000) $2,016 Avg Close $43.60 Range $33.31 - $48.89

Period	Shares	Value ($000)	Average Close	Price Range
Q3 2025	65,756	$4,368	$56.84	$49.38 - $68.26
Q2 2025	91,875	$5,078	$47.99	$39.60 - $57.70
Q1 2025	44,872	$2,170	$41.90	$33.70 - $60.60
Q4 2024	52,239	$2,016	$43.60	$33.31 - $48.89