PROTAGONIST THERAPEUTICS INC

Ticker: PTGX CUSIP: 74366E102 Class: Common Stock

Polar Capital Holdings Plc's Holding History (CIK: 0001837309)

Note: Option positions (PUT/CALL) are excluded.

Q4 2024

Shares 350,000 Value ($000) $13,510 Avg Close $43.60 Range $33.31 - $48.89

Q3 2024

Shares 350,000 Value ($000) $15,750 Avg Close $40.40 Range $32.50 - $48.00

Q1 2022

Shares 303,429 Value ($000) $7,185 Avg Close $28.17 Range $22.56 - $37.05

Q4 2021

Shares 303,429 Value ($000) $10,377 Avg Close $31.61 Range $17.26 - $38.11

Q3 2021

Shares 218,936 Value ($000) $3,880 Avg Close $42.63 Range $12.80 - $50.54

Q2 2021

Shares 119,203 Value ($000) $5,350 Avg Close $33.01 Range $24.14 - $45.93

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2024	350,000	$13,510	$43.60	$33.31 - $48.89
Q3 2024	350,000	$15,750	$40.40	$32.50 - $48.00
Q1 2022	303,429	$7,185	$28.17	$22.56 - $37.05
Q4 2021	303,429	$10,377	$31.61	$17.26 - $38.11
Q3 2021	218,936	$3,880	$42.63	$12.80 - $50.54
Q2 2021	119,203	$5,350	$33.01	$24.14 - $45.93