PROTEOSTASIS THERAPEUTICS IN

CUSIP: 74373B109 Class: COM

RENAISSANCE TECHNOLOGIES LLC's Holding History (CIK: 0001037389)

Note: Option positions (PUT/CALL) are excluded.

Q3 2020
Shares 235,263 Value ($000) $259 Avg Close — Range —
Q2 2020
Shares 189,380 Value ($000) $259 Avg Close — Range —
Q4 2018
Shares 280,900 Value ($000) $910 Avg Close — Range —
Q3 2017
Shares 138,400 Value ($000) $291 Avg Close — Range —
Q2 2016
Shares 19,700 Value ($000) $239 Avg Close — Range —