PUMA BIOTECHNOLOGY INC

Ticker: PBYI CUSIP: 74587V107 Class: Common Stock

WELLS FARGO & COMPANY/MN's Holding History (CIK: 0000072971)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 48,281 Value ($000) $287 Avg Close $5.31 Range $4.58 - $6.27

Q3 2025

Shares 32,531 Value ($000) $173 Avg Close $4.24 Range $3.03 - $6.07

Q2 2025

Shares 28,026 Value ($000) $96 Avg Close $3.19 Range $2.58 - $3.82

Q1 2025

Shares 23,448 Value ($000) $69 Avg Close $3.13 Range $2.69 - $4.06

Q4 2024

Shares 22,929 Value ($000) $70 Avg Close $2.91 Range $2.32 - $3.51

Q3 2024

Shares 16,803 Value ($000) $43 Avg Close $3.03 Range $2.23 - $4.13

Q2 2024

Shares 16,450 Value ($000) $54 Avg Close $4.39 Range $2.81 - $6.06

Q1 2024

Shares 8,316 Value ($000) $44 Avg Close $5.38 Range $4.12 - $7.73

Q4 2023

Shares 311 Value ($000) $1 Avg Close $3.31 Range $2.13 - $4.59

Q3 2023

Shares 295 Value ($000) $1 Avg Close $3.41 Range $2.57 - $4.19

Q2 2023

Shares 289 Value ($000) $1 Avg Close $3.12 Range $2.53 - $3.75

Q1 2023

Shares 272 Value ($000) $1 Avg Close $3.77 Range $2.13 - $4.89

Q4 2022

Shares 267 Value ($000) $1 Avg Close $3.45 Range $2.08 - $5.16

Q3 2022

Shares 260 Value ($000) $1 Avg Close $2.92 Range $2.23 - $4.07

Q2 2022

Shares 253 Value ($000) $1 Avg Close $2.49 Range $1.60 - $3.42

Q1 2022

Shares 140,495 Value ($000) $404 Avg Close $2.59 Range $2.06 - $3.38

Q4 2021

Shares 215,768 Value ($000) $656 Avg Close $4.34 Range $2.78 - $7.11

Q3 2021

Shares 257,025 Value ($000) $1,802 Avg Close $7.49 Range $6.48 - $9.48

Q2 2021

Shares 224,470 Value ($000) $2,062 Avg Close $10.13 Range $8.74 - $11.95

Q1 2021

Shares 218,156 Value ($000) $2,120 Avg Close $11.17 Range $9.19 - $14.14

Q4 2020

Shares 81,140 Value ($000) $833 Avg Close $10.13 Range $7.48 - $13.16

Q3 2020

Shares 101,888 Value ($000) $1,028 Avg Close $10.18 Range $9.04 - $12.90

Q2 2020

Shares 91,504 Value ($000) $955 Avg Close $10.35 Range $6.81 - $13.78

Q1 2020

Shares 91,068 Value ($000) $768 Avg Close $9.72 Range $5.50 - $15.00

Q4 2019

Shares 85,802 Value ($000) $751 Avg Close $8.28 Range $6.26 - $11.10

Q3 2019

Shares 80,796 Value ($000) $871 Avg Close $10.80 Range $8.45 - $13.35

Q2 2019

Shares 65,717 Value ($000) $835 Avg Close $23.03 Range $12.22 - $36.75

Q1 2019

Shares 22,131 Value ($000) $858 Avg Close $30.54 Range $19.86 - $43.90

Q4 2018

Shares 22,267 Value ($000) $454 Avg Close $30.01 Range $17.60 - $47.14

Q3 2018

Shares 22,783 Value ($000) $1,045 Avg Close $48.21 Range $40.45 - $60.95

Q2 2018

Shares 25,451 Value ($000) $1,506 Avg Close $57.95 Range $47.00 - $68.90

Q1 2018

Shares 342,515 Value ($000) $23,309 Avg Close $74.88 Range $56.15 - $101.50

Q4 2017

Shares 524,933 Value ($000) $51,890 Avg Close $111.90 Range $92.36 - $136.90

Q3 2017

Shares 58,551 Value ($000) $7,010 Avg Close $93.01 Range $71.14 - $120.85

Q2 2017

Shares 23,010 Value ($000) $2,011 Avg Close $55.94 Range $28.35 - $92.00

Q1 2017

Shares 24,151 Value ($000) $899 Avg Close $36.49 Range $28.95 - $45.44

Q4 2016

Shares 21,950 Value ($000) $675 Avg Close $43.24 Range $29.85 - $68.05

Q3 2016

Shares 11,315 Value ($000) $759 Avg Close $50.56 Range $28.14 - $73.27

Q2 2016

Shares 8,700 Value ($000) $259 Avg Close $31.26 Range $19.74 - $39.67

Q1 2016

Shares 2,446 Value ($000) $72 Avg Close $45.19 Range $25.20 - $77.99

Q4 2015

Shares 2,232 Value ($000) $175 Avg Close $78.49 Range $56.11 - $94.93

Q3 2015

Shares 2,248 Value ($000) $169 Avg Close $94.57 Range $70.39 - $119.36

Q2 2015

Shares 82,571 Value ($000) $9,411 Avg Close $181.09 Range $112.32 - $244.90

Q1 2015

Shares 196,035 Value ($000) $46,285 Avg Close $213.77 Range $183.50 - $252.92

Q4 2014

Shares 346,552 Value ($000) $65,592 Avg Close $221.87 Range $181.60 - $255.43

Q3 2014

Shares 531,102 Value ($000) $126,704 Avg Close $205.34 Range $57.25 - $279.37

Q2 2014

Shares 453,586 Value ($000) $29,936 Avg Close $71.11 Range $53.63 - $118.22

Q1 2014

Shares 338,082 Value ($000) $35,208 Avg Close $117.54 Range $97.31 - $143.65

Q4 2013

Shares 280,968 Value ($000) $29,088 Avg Close $58.69 Range $33.70 - $112.46

Q3 2013

Shares 319,683 Value ($000) $17,154 Avg Close $53.90 Range $44.39 - $62.66

Q2 2013

Shares 225 Value ($000) $10 Avg Close $35.25 Range $27.40 - $45.69

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	48,281	$287	$5.31	$4.58 - $6.27
Q3 2025	32,531	$173	$4.24	$3.03 - $6.07
Q2 2025	28,026	$96	$3.19	$2.58 - $3.82
Q1 2025	23,448	$69	$3.13	$2.69 - $4.06
Q4 2024	22,929	$70	$2.91	$2.32 - $3.51
Q3 2024	16,803	$43	$3.03	$2.23 - $4.13
Q2 2024	16,450	$54	$4.39	$2.81 - $6.06
Q1 2024	8,316	$44	$5.38	$4.12 - $7.73
Q4 2023	311	$1	$3.31	$2.13 - $4.59
Q3 2023	295	$1	$3.41	$2.57 - $4.19
Q2 2023	289	$1	$3.12	$2.53 - $3.75
Q1 2023	272	$1	$3.77	$2.13 - $4.89
Q4 2022	267	$1	$3.45	$2.08 - $5.16
Q3 2022	260	$1	$2.92	$2.23 - $4.07
Q2 2022	253	$1	$2.49	$1.60 - $3.42
Q1 2022	140,495	$404	$2.59	$2.06 - $3.38
Q4 2021	215,768	$656	$4.34	$2.78 - $7.11
Q3 2021	257,025	$1,802	$7.49	$6.48 - $9.48
Q2 2021	224,470	$2,062	$10.13	$8.74 - $11.95
Q1 2021	218,156	$2,120	$11.17	$9.19 - $14.14
Q4 2020	81,140	$833	$10.13	$7.48 - $13.16
Q3 2020	101,888	$1,028	$10.18	$9.04 - $12.90
Q2 2020	91,504	$955	$10.35	$6.81 - $13.78
Q1 2020	91,068	$768	$9.72	$5.50 - $15.00
Q4 2019	85,802	$751	$8.28	$6.26 - $11.10
Q3 2019	80,796	$871	$10.80	$8.45 - $13.35
Q2 2019	65,717	$835	$23.03	$12.22 - $36.75
Q1 2019	22,131	$858	$30.54	$19.86 - $43.90
Q4 2018	22,267	$454	$30.01	$17.60 - $47.14
Q3 2018	22,783	$1,045	$48.21	$40.45 - $60.95
Q2 2018	25,451	$1,506	$57.95	$47.00 - $68.90
Q1 2018	342,515	$23,309	$74.88	$56.15 - $101.50
Q4 2017	524,933	$51,890	$111.90	$92.36 - $136.90
Q3 2017	58,551	$7,010	$93.01	$71.14 - $120.85
Q2 2017	23,010	$2,011	$55.94	$28.35 - $92.00
Q1 2017	24,151	$899	$36.49	$28.95 - $45.44
Q4 2016	21,950	$675	$43.24	$29.85 - $68.05
Q3 2016	11,315	$759	$50.56	$28.14 - $73.27
Q2 2016	8,700	$259	$31.26	$19.74 - $39.67
Q1 2016	2,446	$72	$45.19	$25.20 - $77.99
Q4 2015	2,232	$175	$78.49	$56.11 - $94.93
Q3 2015	2,248	$169	$94.57	$70.39 - $119.36
Q2 2015	82,571	$9,411	$181.09	$112.32 - $244.90
Q1 2015	196,035	$46,285	$213.77	$183.50 - $252.92
Q4 2014	346,552	$65,592	$221.87	$181.60 - $255.43
Q3 2014	531,102	$126,704	$205.34	$57.25 - $279.37
Q2 2014	453,586	$29,936	$71.11	$53.63 - $118.22
Q1 2014	338,082	$35,208	$117.54	$97.31 - $143.65
Q4 2013	280,968	$29,088	$58.69	$33.70 - $112.46
Q3 2013	319,683	$17,154	$53.90	$44.39 - $62.66
Q2 2013	225	$10	$35.25	$27.40 - $45.69