PUMA BIOTECHNOLOGY INC

Ticker: PBYI CUSIP: 74587V107 Class: Common Stock

LOOMIS SAYLES & CO L P's Holding History (CIK: 0000312348)

Note: Option positions (PUT/CALL) are excluded.

Q1 2015

Shares 62,796 Value ($000) $14,827 Avg Close $213.77 Range $183.50 - $252.92

Q4 2014

Shares 67,932 Value ($000) $12,857 Avg Close $221.87 Range $181.60 - $255.43

Q3 2014

Shares 87,687 Value ($000) $20,919 Avg Close $205.34 Range $57.25 - $279.37

Q4 2013

Shares 24,233 Value ($000) $2,509 Avg Close $58.69 Range $33.70 - $112.46

Q3 2013

Shares 32,347 Value ($000) $1,736 Avg Close $53.90 Range $44.39 - $62.66

Q2 2013

Shares 29,616 Value ($000) $1,314 Avg Close $35.25 Range $27.40 - $45.69

Period	Shares	Value ($000)	Average Close	Price Range
Q1 2015	62,796	$14,827	$213.77	$183.50 - $252.92
Q4 2014	67,932	$12,857	$221.87	$181.60 - $255.43
Q3 2014	87,687	$20,919	$205.34	$57.25 - $279.37
Q4 2013	24,233	$2,509	$58.69	$33.70 - $112.46
Q3 2013	32,347	$1,736	$53.90	$44.39 - $62.66
Q2 2013	29,616	$1,314	$35.25	$27.40 - $45.69