PUMA BIOTECHNOLOGY INC

Ticker: PBYI CUSIP: 74587V107 Class: Common Stock

FIRST MANHATTAN CO. LLC.'s Holding History (CIK: 0000728083)

Note: Option positions (PUT/CALL) are excluded.

Q1 2019

Shares 425,900 Value ($000) $16,520 Avg Close $30.54 Range $19.86 - $43.90

Q4 2018

Shares 436,200 Value ($000) $8,876 Avg Close $30.01 Range $17.60 - $47.14

Period	Shares	Value ($000)	Average Close	Price Range
Q1 2019	425,900	$16,520	$30.54	$19.86 - $43.90
Q4 2018	436,200	$8,876	$30.01	$17.60 - $47.14