PUMA BIOTECHNOLOGY INC

Ticker: PBYI CUSIP: 74587V107 Class: Common Stock

Capital International, Inc./CA/'s Holding History (CIK: 0000895213)

Note: Option positions (PUT/CALL) are excluded.

Q4 2015

Shares 85,450 Value ($000) $6,699 Avg Close $78.49 Range $56.11 - $94.93

Q3 2015

Shares 85,450 Value ($000) $6,440 Avg Close $94.57 Range $70.39 - $119.36

Q2 2015

Shares 53,950 Value ($000) $6,299 Avg Close $181.09 Range $112.32 - $244.90

Q1 2015

Shares 43,700 Value ($000) $10,318 Avg Close $213.77 Range $183.50 - $252.92

Q4 2014

Shares 37,800 Value ($000) $7,154 Avg Close $221.87 Range $181.60 - $255.43

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2015	85,450	$6,699	$78.49	$56.11 - $94.93
Q3 2015	85,450	$6,440	$94.57	$70.39 - $119.36
Q2 2015	53,950	$6,299	$181.09	$112.32 - $244.90
Q1 2015	43,700	$10,318	$213.77	$183.50 - $252.92
Q4 2014	37,800	$7,154	$221.87	$181.60 - $255.43